Bromocriptine Response in Pathological Hyperprolactinemia: A 34 Year Follow-Up of a Homogeneous Population of 827 Patients
نویسنده
چکیده
827 patients with symptomatic pathological hyperprolactinemia were treated with bromocriptine. The evaluation, treatment, and follow-up was by a single individual, making this a large and unique homogeneous group for purposes of treatment evaluation.
منابع مشابه
The effect of Vitex Agnus castus extract on blood level of prolactin, & compare of its effects on the Lipids level with those of Bromocriptine and Dostinex in women with hyperprolactinemia
Introduction Hyperprolactinemia in women results in menstrual disorders, irregular ovulation, amenorrhea, and reduction of progesterone Level after ovulation, due to corpus luteum failure. This study aimed at comparing the effect of Vitagnus fruit extract on blood prolactin level and its effect on altered serum lipids in Hyperprolactinemic women with Bromocriptine and Dustinex. Materials and M...
متن کاملParadoxical prolactin response to growth hormone-releasing hormone in a patient with hyperprolactinemia and empty sella.
In a 30-year-old woman with amenorrhea due to hyperprolactinemia, serum PRL increased to twice the basal amount in response to growth hormone-releasing hormone (GHRH). Roentgenological studies revealed no pituitary adenoma but empty sella. Bromocriptine therapy normalized serum PRL and made the paradoxical response to GHRH disappear. The paradoxical response did not occur in any of eight other ...
متن کاملCabergoline in the treatment of hyperprolactinemia: a study in 455 patients.
Cabergoline is a new long-acting dopamine agonist that is very effective and well tolerated in patients with pathological hyperprolactinemia. The aim of this study was to examine, in a very large number of hyperprolactinemic patients, the ability to normalize PRL levels with cabergoline, to determine the effective dose and tolerance, and to assess the effect on clinical symptoms, tumor shrinkag...
متن کاملEffect of bromocriptine and pergolide on pituitary tumor size and serum prolactin.
Forty-two patients with elevated serum prolactin were treated in a randomized, open-label trial with the conventional ergot bromocriptine, or a new ergot pergolide. Before treatment, the patients underwent thorough endocrine evaluation and computed tomographic scan. All patients had prolactin levels greater than 25 ng/ml, and 27 patients had a pituitary mass. Follow-up studies performed after 6...
متن کاملLong-Term Clinical Outcomes of Invasive Giant Prolactinomas after a Mean Ten-Year Followup
Objective. The aim of this study is to observe clinical outcomes after more than ten years of followup in a group of patients with invasive giant prolactinomas (IGPs) treated with dopamine agonists (DAs). Methods. Twenty-five patients met the criteria of IGPs, among which 16 patients primarily received bromocriptine (BRC) and the other nine had undergone unsuccessful microsurgery prior to BRC t...
متن کامل